FOCUSED ASSAY

IFN-1 Test

Measure interferon pathway activity to identify SLE patients more likely to experience moderate to severe disease.

Contact Us

Type 1Interferon results

DxTerity's IFN-1 Test uses a simple fingerstick blood collection conducted at your doctor's office. Measure your IFN-1 levels and know your risks for SLE disease progression.

Multiple RNA measurements

Indication of SLE disease severity

Changes in IFN-1 Level

The DxTerity IFN-1 Test was developed and validated by DxTerity’s CAP-accredited, CLIA-certified laboratory. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CLINICAL EVIDENCE

What the Type 1 Interferon (IFN-1) research shows

>50%

of SLE patients show elevated IFN-1 expression

IFN-1 High

strong correlation to more severe disease

12

published peer-reviewed studies

Precision medicine for autoimmune disease

DxTerity is at the forefront of diagnostic test innovation, addressing the unmet need of those suffering from immune-mediated disease. We are dedicated to using the latest technologies and advancements to deliver clinically relevant, precision diagnostic tools to help healthcare providers improve patient outcomes. Unlike precision medicine for cancer which primarily relies on DNA mutation testing, autoimmune disease looks at RNA, because its dynamic nature provides insight into biological pathway activity that drives disease.

A therapeutic evolution

New treatments target the biological pathways that drive the development of autoimmune disease. Examples include therapies which block Type-1 Interferon signaling, monoclonal antibodies targeting the B-Cell Activating Factor (BAFF) and its cellular receptor, or CAR-T cellular therapeutics which look to faciliate total iimmune system reset and disease cure..

Type 1 Interferon (IFN-1)

Scientific literature has shown IFN-1 activity levels may provide information to help guide treatment decisions. IFN-1 High patients show increased risk of developing severe disease, and decreased likelihood of responding to standard of care. Patients with higher IFN-1 levels have been shown to have an increased response to IFN-1 targeted therapeutic pathways.

Resources & downloads

Eular IFN-1 Poster

Test performance and analytical validation data.

Download PDF →

Publications

Helpful Lupus Educational Resources

Download PDF

Test Requisition Form

Forms and instructions for ordering access.

Download PDF →

Test Report Example

Laboratory Report Example

Download PDF →

Experience Simplicity

“The ease of testing from the physicians office is a real difference maker.”

Lupus Patient

Contact us about testing for IFN-1

Contact Us

Stay in the know.

Get the latest updates and news.

DxTerity’s patient-focused mission is to bring the power of at-home RNA-based genomic monitoring to improve the management of immune-mediated diseases and overall patient well-being.

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Development Services

Technology

News

Contact us

FOCUSED ASSAY

IFN-1 Test

Measure interferon pathway activity to identify SLE patients more likely to experience moderate to severe disease.

Contact us

Type 1Interferon results

DxTerity's IFN-1 Test uses a simple fingerstick blood collection conducted at your doctor's office. Measure your IFN-1 levels and know your risks for SLE disease progression.

Multiple RNA measurements

Measures 4 messenger RNAs (mRNAs) associated with Type 1 Interferon (IFN-1) activity.

Indication of SLE disease severity

Prognostic markers for increased risk of moderate to severe Systemic Lupus Erythematous (SLE) .

Changes in IFN-1 Level

Identify changes in IFN-1 levels

Patient Result Graph

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Physician Requisition

The DxTerity IFN-1 Test was developed and validated by DxTerity’s CAP-accredited, CLIA-certified laboratory. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CLINICAL EVIDENCE

What the Type 1 Interferon (IFN-1) research shows

>50%

of SLE patients show elevated IFN-1 expression

IFN-1 High

strong correlation to more severe disease

12

published peer-reviewed studies

Precision medicine for autoimmune disease

DxTerity is at the forefront of diagnostic test innovation, addressing the unmet need of those suffering from immune-mediated disease. We are dedicated to using the latest technologies and advancements to deliver clinically relevant, precision diagnostic tools to help healthcare providers improve patient outcomes. Unlike precision medicine for cancer which primarily relies on DNA mutation testing, autoimmune disease looks at RNA, because its dynamic nature provides insight into biological pathway activity that drives disease.

A therapeutic evolution

New treatments target the biological pathways that drive the development of autoimmune disease. Examples include therapies which block Type-1 Interferon signaling, monoclonal antibodies targeting the B-Cell Activating Factor (BAFF) and its cellular receptor, or CAR-T cellular therapeutics which look to facilitate total immune system reset and disease cure..

Type 1 Interferon (IFN-1)

Scientific literature has shown IFN-1 activity levels may provide information to help guide treatment decisions. IFN-1 High patients show increased risk of developing severe disease, and decreased likelihood of responding to standard of care. Patients with higher IFN-1 levels have been shown to have an increased response to IFN-1 targeted therapeutic pathways.

Resources & downloads

Eular IFN-1 Poster

Test performance and analytical validation data.

Download PDF →

Publications

Helpful Lupus Educational Resources

Download PDF →

Test Requisition Form

Forms and instructions for ordering access.

Download PDF →

Test Report Example

Laboratory Report Example

Download PDF →

Experience Simplicity

“The ease of testing from the physicians office is a real difference maker.”

Lupus Patient

Contact us about testing for IFN-1

Contact Us

Stay in the know.

Get the latest updates and news.

DxTerity’s patient-focused mission is to bring the power of at-home RNA-based genomic monitoring to improve the management of immune-mediated diseases and overall patient well-being.