Type-1 Interferon Test for Lupus

Type-1 Interferon (IFN-1) activity is an essential component in your patients’ immune response to infection; however, persistently high IFN-1 activity has been shown to play a central role in the development of Systemic Lupus Erythematosus (SLE) disease and progression. An estimated 50% of SLE patients overexpress IFN-1 and disease severity correlates with expression level. Overexpression of IFN-1 has been shown to lead to an increased risk for disease complications and progression to Lupus Nephritis. DxTerity’s IFN-1 Test is designed to measure IFN-1 activity prior to starting therapy and to monitor IFN-1 levels in response to therapy.